Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19615611 | 1.00 | RAB9A (0.46) | RAB9AALDH1A1NPC1KDM4EALOX15 | |
| SCHEMBL19631864 | 0.89 | KDM4C (0.48) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL19615620 | 0.89 | KDM4C (0.48) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL19615821 | 0.85 | RAB9A (0.50) | RAB9AALDH1A1NPC1KDM4EALOX15 | |
| SCHEMBL19615810 | 0.83 | KDM4E (0.55) | RAB9AALDH1A1NPC1KDM4EALOX15 | |
| SCHEMBL19631865 | 0.83 | KDM4E (0.55) | RAB9AALDH1A1NPC1KDM4EALOX15 | |
| SCHEMBL19615942 | 0.79 | CA1 (0.51) | RAB9AALDH1A1NPC1KDM4EALOX15 | |
| SCHEMBL19629777 | 0.79 | CA1 (0.51) | RAB9AALDH1A1NPC1KDM4EALOX15 | |
| SCHEMBL19615569 | 0.79 | KDM4E (0.49) | RAB9AALDH1A1NPC1KDM4EALOX15 | |
| SCHEMBL19632252 | 0.78 | NPC1 (0.52) | RAB9AALDH1A1NPC1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198785-A1 | OXIME DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASE KDM4C | IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |