Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.61 |
| ▸ | KDM5A | P29375 | 5/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 3/20 | 0.45 |
| ▸ | RXRB | P28702 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19615658 | 0.87 | KDM5B (0.56) | NR4A2KDM5AKDM4CKDM5BKDM2B | |
| SCHEMBL19615548 | 0.86 | NR4A2 (0.56) | NR4A2KDM5AKDM4CKDM5BPPARA | |
| SCHEMBL19616535 | 0.86 | NR4A2 (0.56) | NR4A2KDM5AKDM4CKDM5BPPARA | |
| SCHEMBL19632107 | 0.80 | NR4A2 (0.47) | NR4A2KDM5AKDM4CKDM5BPPARA | |
| SCHEMBL19615520 | 0.79 | NR4A2 (0.61) | NR4A2KDM5AKDM4CKDM5BPPARA | |
| SCHEMBL19631979 | 0.78 | KDM4E (0.51) | KDM5AKDM4CKDM5BKDM2BNPC1 | |
| SCHEMBL19615732 | 0.78 | KDM4E (0.51) | KDM5AKDM4CKDM5BKDM2BNPC1 | |
| SCHEMBL19615660 | 0.78 | NR4A2 (0.60) | NR4A2KDM5AKDM4CKDM5BPPARA | |
| SCHEMBL19631870 | 0.78 | KDM4C (0.48) | NR4A2KDM5AKDM4CKDM5BPPARA | |
| SCHEMBL6412631 | 0.78 | NR4A2 (1.00) | NR4A2PPARAMAOBPARP10RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198785-A1 | OXIME DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASE KDM4C | IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |