Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | AR | P10275 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6845447 | 0.85 | CYP19A1 (0.62) | PGRCYP3A4ARALDH1A1CYP2C19 | |
| SCHEMBL6845448 | 0.85 | CYP19A1 (0.62) | PGRCYP3A4ARALDH1A1CYP2C19 | |
| SCHEMBL149089 | 0.83 | PGR (0.70) | PGRCYP3A4ARALDH1A1CYP2C19 | |
| SCHEMBL5925193 | 0.83 | PGR (0.70) | PGRCYP3A4ARALDH1A1CYP2C19 | |
| SCHEMBL11594373 | 0.80 | PGR (0.59) | PGRCYP3A4ARALDH1A1CYP2C19 | |
| SCHEMBL22152118 | 0.80 | CYP19A1 (0.67) | PGRCYP3A4ARALDH1A1CYP2C19 | |
| SCHEMBL3934288 | 0.79 | MEN1 (0.70) | PGRCYP3A4ARALDH1A1CYP2C19 | |
| SCHEMBL3934282 | 0.79 | MEN1 (0.70) | PGRCYP3A4ARALDH1A1CYP2C19 | |
| SCHEMBL11648110 | 0.79 | PGR (0.56) | PGRCYP3A4ARALDH1A1CYP2C19 | |
| SCHEMBL3939910 | 0.78 | PGR (0.67) | PGRCYP3A4ARALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190153023-A1 | Steroid 6.7.Beta.-Epoxides as Chemical Intermediates | NZP UK Limited (GB) | 2019-05-23 | — | — | US | disclosed |
| WO-2017199039-A1 | STEROID 6.7.BETA.-EPOXIDES AS CHEMICAL INTERMEDIATES | NZP UK Limited (GB) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190153023-A1 | Steroid 6.7.Beta.-Epoxides as Chemical Intermediates | CYP7A1, CYP7B1, CYP21A2 | PGR 216/4885CYP3A4 57/4885AR 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.