Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19632554 | 0.88 | KDM4E (0.45) | CNR2KDM4ELMNAMAPTHPGD | |
| SCHEMBL21650373 | 0.84 | ALDH1A1 (0.50) | CNR2KDM4ELMNAMAPTHPGD | |
| SCHEMBL19632243 | 0.83 | CNR2 (0.39) | CNR2KDM4ELMNAMAPTHPGD | |
| SCHEMBL19632552 | 0.82 | KDM4E (0.43) | CNR2KDM4ELMNAMAPTHPGD | |
| SCHEMBL19632274 | 0.82 | CNR2 (0.38) | CNR2KDM4ELMNAMAPTHPGD | |
| SCHEMBL12629359 | 0.79 | KDM4E (0.53) | CNR2KDM4ELMNAMAPTHPGD | |
| SCHEMBL13512747 | 0.79 | CNR2 (0.50) | CNR2KDM4ELMNAMAPTHPGD | |
| SCHEMBL1979579 | 0.75 | CNR2 (0.67) | CNR2KDM4ELMNAMAPTHPGD | |
| SCHEMBL29849978 | 0.75 | CNR2 (0.67) | CNR2KDM4ELMNAMAPTHPGD | |
| SCHEMBL20022363 | 0.74 | CNR2 (0.55) | CNR2KDM4ELMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255736-A1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | MERCK PATENT GMBH (DE) | 2020-08-13 | — | — | US | disclosed |
| EP-3458548-B1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | MERCK PATENT GMBH (DE) | 2020-01-29 | — | — | EP | disclosed |
| WO-2017198584-A1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |