Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.36 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19632274 | 0.92 | CNR2 (0.38) | CNR2KDM4EMAPTLMNANPC1 | |
| SCHEMBL19632272 | 0.90 | KDM4E (0.39) | CNR2KDM4EMAPTLMNANPC1 | |
| SCHEMBL19632429 | 0.85 | NPC1 (0.38) | CNR2KDM4ELMNANPC1PTGER4 | |
| SCHEMBL19632555 | 0.83 | CNR2 (0.44) | CNR2KDM4EMAPTLMNANPC1 | |
| SCHEMBL24034833 | 0.82 | KDM4E (0.38) | CNR2KDM4EMAPTLMNANPC1 | |
| SCHEMBL19632206 | 0.82 | KDM4E (0.38) | CNR2KDM4EMAPTLMNANPC1 | |
| SCHEMBL17540420 | 0.79 | NPC1 (0.46) | CNR2KDM4EMAPTLMNANPC1 | |
| SCHEMBL17540422 | 0.78 | NPC1 (0.37) | MAPTLMNANPC1PTGER4HPGD | |
| SCHEMBL13512747 | 0.78 | CNR2 (0.50) | CNR2KDM4EMAPTLMNANPC1 | |
| SCHEMBL21650373 | 0.78 | ALDH1A1 (0.50) | CNR2KDM4EMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255736-A1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | MERCK PATENT GMBH (DE) | 2020-08-13 | — | — | US | disclosed |
| EP-3458548-B1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | MERCK PATENT GMBH (DE) | 2020-01-29 | — | — | EP | disclosed |
| WO-2017198584-A1 | POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |