Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 19/20 | 0.47 |
| ▸ | PPARA | Q07869 | 17/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633046 | 1.00 | MAOA (0.48) | MAOAMAOBPPARGPPARA | |
| SCHEMBL19632623 | 1.00 | MAOA (0.48) | MAOAMAOBPPARGPPARA | |
| SCHEMBL19632508 | 0.88 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL19632687 | 0.88 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL19632603 | 0.87 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL19632509 | 0.87 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL19633140 | 0.85 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL19632747 | 0.85 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL19632749 | 0.85 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL19633051 | 0.83 | PPARG (0.47) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197488-A1 | LIBRARIES OF DIVERSE MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2017-11-23 | — | — | WO | disclosed |