SCHEMBL19632747

SCHEMBL19632747

C=CCOC(=O)C(Cc1ccccc1)Oc1cccc(CO)c1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.51
PPARA Q07869 18/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19632749 1.00 PPARG (0.51) PPARGPPARA
SCHEMBL19633140 1.00 PPARG (0.51) PPARGPPARA
SCHEMBL19633176 0.90 PPARG (0.47) PPARGPPARA
SCHEMBL19633051 0.90 PPARG (0.47) PPARGPPARA
SCHEMBL19632509 0.89 PPARG (0.48) PPARGPPARA
SCHEMBL19632603 0.89 PPARG (0.48) PPARGPPARA
SCHEMBL19633053 0.89 PPARG (0.67) PPARGPPARA
SCHEMBL19633174 0.89 PPARG (0.67) PPARGPPARA
SCHEMBL19632623 0.85 MAOA (0.48) PPARGPPARA
SCHEMBL19632637 0.85 MAOA (0.48) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017197488-A1 LIBRARIES OF DIVERSE MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME CYCLENIUM PHARMA INC. (CA) 2017-11-23 WO disclosed