Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 3/20 | 0.51 |
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15259641 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2AMAPTL3MBTL1 | |
| SCHEMBL11526133 | 0.79 | CLCN2 (0.53) | ABCC1MASP2CLCN2ALDH1A1KDM4E | |
| SCHEMBL3627546 | 0.79 | MASP2 (0.62) | ABCC1MASP2ALDH1A1KDM4EPOLB | |
| SCHEMBL8686783 | 0.78 | CLCN2 (0.46) | ABCC1MASP2CLCN2ALDH1A1KDM4E | |
| SCHEMBL11526676 | 0.78 | CLCN2 (0.51) | ABCC1MASP2CLCN2ALDH1A1KDM4E | |
| SCHEMBL1355391 | 0.76 | ALDH1A1 (0.52) | CLCN2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL15777340 | 0.75 | PARP1 (0.46) | CLCN2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL22289678 | 0.75 | SIRT2 (0.51) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL14058983 | 0.74 | KDM4E (0.47) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL29630852 | 0.73 | NPC1 (0.56) | ALDH1A1KDM4EKMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |