Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19708072 | 0.90 | MEN1 (0.66) | KMT2AMEN1TDP1LMNAMAPT | |
| SCHEMBL8345899 | 0.75 | MCHR1 (0.56) | KMT2AMEN1LMNAMAPTNPC1 | |
| SCHEMBL19707272 | 0.75 | KMT2A (0.65) | KMT2AMEN1TDP1LMNAMAPT | |
| SCHEMBL19427499 | 0.75 | NPC1 (0.63) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL5454456 | 0.75 | HTT (0.51) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL19825005 | 0.75 | NPC1 (0.63) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL18614121 | 0.73 | KMT2A (0.55) | KMT2AMEN1FPR2LMNAMAPT | |
| SCHEMBL5702218 | 0.73 | RNF4 (0.51) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15984777 | 0.73 | SMN1; SMN2 (0.62) | KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7539909 | 0.73 | KMT2A (0.47) | KMT2AMEN1MAOAMAOBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201187-A1 | LIM KINASE INHIBITORS | VIRONGY, LLC (US) | 2017-11-23 | — | — | WO | disclosed |