Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347783 | 0.92 | MEN1 (0.65) | MCHR1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12963481 | 0.91 | MCHR1 (0.54) | MCHR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12933366 | 0.88 | MCHR1 (0.48) | MCHR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12963493 | 0.82 | MEN1 (0.51) | MCHR1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12933367 | 0.79 | LMNA (0.47) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL13074283 | 0.79 | QPCT (0.51) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL1058480 | 0.77 | HDAC1 (0.59) | MCHR1 | |
| SCHEMBL8348684 | 0.77 | MCHR1 (0.67) | MCHR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12963479 | 0.77 | SMN1; SMN2 (0.49) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6108187 | 0.76 | MCHR1 (0.53) | MCHR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069823-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2004-08-19 | — | — | WO | disclosed |