Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19708072 | 0.81 | MEN1 (0.66) | KMT2AMEN1TDP1LMNAMAPT | |
| SCHEMBL7534719 | 0.78 | ALOX5 (0.39) | KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL19632886 | 0.73 | KMT2A (0.55) | KMT2AMEN1TDP1LMNAMAPT | |
| SCHEMBL19707272 | 0.72 | KMT2A (0.65) | KMT2AMEN1TDP1LMNAMAPT | |
| SCHEMBL17932837 | 0.69 | USP2 (0.63) | KMT2AMEN1USP2HSD17B10LMNA | |
| SCHEMBL148345 | 0.69 | MEN1 (0.68) | KMT2AMEN1TDP1MAOAMAOB | |
| SCHEMBL8541703 | 0.69 | MEN1 (0.68) | KMT2AMEN1TDP1MAOAMAOB | |
| SCHEMBL19707279 | 0.68 | MEN1 (0.43) | KMT2AMEN1TDP1USP2HSD17B10 | |
| SCHEMBL31144832 | 0.68 | MEN1 (0.57) | KMT2AMEN1TDP1MAPTHPGD | |
| SCHEMBL19707215 | 0.68 | MEN1 (0.49) | KMT2AMEN1TDP1LMNAF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200395-A1 | UREA DERIVATIVES AS INHIBITORS OF CCR-3 RECEPTOR | KIRIN BEER KABUSHIKI KAISHA (JP) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009088-A1 | UREA DERIVATIVES AS INHIBITORS OF CCR-3 RECEPTOR | KIRIN BEER KABUSHIKI KAISHA (JP) | 2001-02-08 | — | — | WO | disclosed |