Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.52 |
| ▸ | PDE8A | O60658 | 5/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633384 | 0.93 | CDK1 (0.50) | CDK1PDE8ACFTRYTHDC1HPRT1 | |
| SCHEMBL985545 | 0.81 | ADCY5 (0.63) | ADORA2AADORA1ADCY5 | |
| SCHEMBL3441081 | 0.78 | CDK1 (0.64) | CDK1PDE8AADORA3ADORA2AADORA1 | |
| SCHEMBL24476374 | 0.78 | HDAC1 (0.53) | YTHDC1HPRT1HDAC1HDAC2HDAC3 | |
| SCHEMBL28654978 | 0.78 | HDAC1 (0.53) | YTHDC1HPRT1HDAC1HDAC2HDAC3 | |
| SCHEMBL10262713 | 0.78 | HDAC1 (0.53) | HDAC1HDAC2HDAC3HDAC10HDAC8 | |
| SCHEMBL19553686 | 0.77 | CDK1 (0.49) | CDK1PDE8ACFTRYTHDC1HDAC1 | |
| SCHEMBL2060052 | 0.77 | YTHDC1 (0.57) | PDE8AYTHDC1 | |
| SCHEMBL19539867 | 0.76 | YTHDC1 (0.74) | PDE8AYTHDC1HDAC1HDAC2HDAC3 | |
| SCHEMBL14024978 | 0.76 | ADORA2A (0.62) | CDK1PDE8AHDAC1HDAC2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197624-A1 | PURINE-SCAFFOLD TLR7 LIGANDS AND CONJUGATE THEREOF | SHENZHEN HORNETCORN BIOTECHNOLOGY COMPANY,CO., LTD (CN) | 2017-11-23 | — | — | WO | disclosed |