Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 5/20 | 0.45 |
| ▸ | AMPD1 | P23109 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.42 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.42 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17078412 | 0.88 | HDAC1 (0.51) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL19633384 | 0.83 | CDK1 (0.50) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL28664886 | 0.82 | HDAC1 (0.59) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL28662851 | 0.81 | AMPD1 (0.43) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL28657767 | 0.81 | AMPD1 (0.43) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8464465 | 0.79 | TK1 (0.51) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL19633358 | 0.78 | CDK1 (0.52) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL5161283 | 0.78 | HDAC1 (0.49) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL944935 | 0.75 | P2RX7 (0.46) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL12537333 | 0.75 | P2RX7 (0.50) | HDAC1HDAC2HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113645977-A | Compounds, compositions and methods for treatment of disease | F-星治疗公司 | 2021-11-12 | — | — | CN | disclosed |