Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 3/20 | 0.53 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.53 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.53 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633550 | 0.89 | PTK6 (0.57) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633568 | 0.88 | GAK (0.58) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633566 | 0.87 | SIRT2 (0.47) | GAKSIRT2ABCG2EGFRKDR | |
| SCHEMBL19633676 | 0.86 | GAK (0.68) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633622 | 0.85 | HTR1A (0.56) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633682 | 0.84 | GSK3A (0.52) | GAKSIRT2KDRALKAPP | |
| SCHEMBL19633703 | 0.84 | GAK (0.60) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633519 | 0.83 | GAK (0.57) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633545 | 0.82 | KMT2A (0.49) | SIRT2ABCG2ALKPTK6ERBB2 | |
| SCHEMBL19633687 | 0.82 | ERBB2 (0.49) | GAKRIPK2COQ8ANLKSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |