Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 6/20 | 0.60 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.60 |
| ▸ | COQ8A | Q8NI60 | 2/20 | 0.60 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.57 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.55 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633676 | 0.93 | GAK (0.68) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633568 | 0.91 | GAK (0.58) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633622 | 0.88 | HTR1A (0.56) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633519 | 0.87 | GAK (0.57) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633513 | 0.86 | GAK (0.56) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633550 | 0.86 | PTK6 (0.57) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL30420470 | 0.86 | GAK (0.67) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL19633636 | 0.86 | FBP1 (0.51) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL21121509 | 0.85 | HTT (0.64) | GAKRIPK2COQ8ANLKHTR1A | |
| SCHEMBL21121679 | 0.85 | HTT (0.64) | GAKRIPK2COQ8ANLKHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |