Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | FADS1 | O60427 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633576 | 0.93 | EGFR (0.48) | PTK6EGFRALKMAOBAPP | |
| SCHEMBL19633566 | 0.88 | SIRT2 (0.47) | EGFRALKKDRAPPNR4A2 | |
| SCHEMBL19633550 | 0.86 | PTK6 (0.57) | PTK6EGFRALKMAOBCTSV | |
| SCHEMBL19633636 | 0.85 | FBP1 (0.51) | PTK6EGFRALKAPPNR4A2 | |
| SCHEMBL19633565 | 0.84 | MAOB (0.57) | PTK6EGFRMAOBGAK | |
| SCHEMBL19633548 | 0.83 | GAK (0.48) | EGFRALKKDRAPPNR4A2 | |
| SCHEMBL15923162 | 0.82 | PTK6 (0.67) | PTK6EGFRALKCTSVCTSL | |
| SCHEMBL31197402 | 0.82 | PTK6 (0.67) | PTK6EGFRALKCTSVCTSL | |
| SCHEMBL19633632 | 0.82 | GAK (0.62) | EGFRGAK | |
| SCHEMBL19633733 | 0.82 | GAK (0.45) | EGFRALKMAPTKDRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |