Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923328 | 0.87 | MC4R (0.72) | MC4RDPP4SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL16509737 | 0.85 | DPP4 (0.75) | MC4RDPP4SLC6A2SLC6A3CYP1A2 | |
| SCHEMBL3470666 | 0.84 | DPP4 (0.73) | MC4RDPP4KCNQ2RAB9APARP1 | |
| SCHEMBL8278787 | 0.84 | DPP4 (0.73) | MC4RDPP4KCNQ2RAB9APARP1 | |
| SCHEMBL2594475 | 0.83 | CXCL8 (0.47) | MC4RDPP4KCNQ2RAB9APARP1 | |
| SCHEMBL14451970 | 0.82 | DPP4 (0.50) | MC4RDPP4KCNQ2RAB9APARP1 | |
| SCHEMBL8276878 | 0.82 | DPP4 (0.50) | MC4RDPP4KCNQ2RAB9APARP1 | |
| SCHEMBL14438312 | 0.81 | ADRB2 (0.56) | MC4RDPP4KCNQ2RAB9APARP1 | |
| SCHEMBL14438301 | 0.81 | ADRB2 (0.56) | MC4RDPP4KCNQ2RAB9APARP1 | |
| SCHEMBL14438308 | 0.81 | ADRB2 (0.56) | MC4RDPP4KCNQ2RAB9APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |