Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634248 | 0.90 | KDM4E (0.36) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL19634304 | 0.86 | ACLY (0.35) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL20256415 | 0.83 | HTR2A (0.38) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL20256744 | 0.83 | GAA (0.38) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL20256934 | 0.83 | CYP1A2 (0.38) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL19634258 | 0.82 | HTR2A (0.38) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL20256322 | 0.81 | SCN8A (0.51) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL20256421 | 0.81 | HTR2A (0.38) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL26184797 | 0.81 | HTR2A (0.38) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL19634090 | 0.81 | HTR2A (0.38) | HTR2ASLC6A4KCNH2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |