Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795881 | 0.87 | HDAC4 (0.54) | ALDH1A1HDAC4DRD2HPGDSMN1; SMN2 | |
| SCHEMBL14640651 | 0.86 | NAMPT (0.49) | ALDH1A1LMNAMAPTCA1CA2 | |
| SCHEMBL4695349 | 0.85 | NAMPT (0.54) | ALDH1A1MAPTCA1CA2TDP1 | |
| SCHEMBL23471148 | 0.84 | CYP4F2 (0.55) | ALDH1A1CYP4A11CYP4F2MAPTPOLB | |
| SCHEMBL6834844 | 0.83 | DRD2 (0.64) | ALDH1A1MAPTCA1CA2MEN1 | |
| SCHEMBL28351759 | 0.82 | CA1 (0.52) | ALDH1A1CYP4A11LMNAMAPTCA1 | |
| SCHEMBL21015888 | 0.82 | HDAC4 (0.46) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL15768278 | 0.81 | MEN1 (0.57) | ALDH1A1LMNAMAPTPOLBMEN1 | |
| SCHEMBL13253174 | 0.81 | ALDH1A1 (0.60) | ALDH1A1CYP4A11CYP4F2LMNAMAPT | |
| SCHEMBL10076226 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHDAC4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |