Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634457 | 0.85 | HPGD (0.59) | HPGDALDH1A1HSD17B10NAMPTLIPG | |
| SCHEMBL21015850 | 0.82 | HPGD (0.55) | HPGDALDH1A1HSD17B10NAMPTLIPG | |
| SCHEMBL19634405 | 0.79 | NAMPT (0.49) | ALDH1A1NAMPTL3MBTL1HTR1A | |
| SCHEMBL8244797 | 0.79 | HPGD (0.62) | HPGDALDH1A1HSD17B10TSHRHRH3 | |
| SCHEMBL8430053 | 0.77 | HPGD (0.68) | HPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL12131750 | 0.76 | ERCC1 (0.70) | HPGDERCC1ERCC4MAPTCA1 | |
| SCHEMBL12569603 | 0.74 | ALDH1A1 (0.71) | HPGDALDH1A1HSD17B10MAPTL3MBTL1 | |
| SCHEMBL19634681 | 0.74 | HPGD (0.63) | HPGDALDH1A1HSD17B10HRH3 | |
| SCHEMBL13848261 | 0.74 | ERCC1 (0.58) | ALDH1A1ERCC1ERCC4MAPTCA12 | |
| SCHEMBL4562855 | 0.74 | KMT2A (0.66) | ALDH1A1ERCC1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |