Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634707 | 0.86 | MEN1 (0.60) | MEN1KMT2AKDM4EALDH1A1KCNH2 | |
| SCHEMBL19634410 | 0.83 | DRD2 (0.50) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL3074396 | 0.82 | MEN1 (0.68) | MEN1KMT2AKDM4EALDH1A1KCNH2 | |
| SCHEMBL19634400 | 0.82 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1KCNH2GPR183 | |
| SCHEMBL10826271 | 0.81 | POLB (0.61) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL18765947 | 0.80 | HPGD (0.62) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL25710940 | 0.80 | HPGD (0.68) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL2377726 | 0.80 | HRH3 (0.64) | MEN1KMT2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL23471231 | 0.79 | KMT2A (0.54) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL507164 | 0.79 | HPGD (0.71) | MEN1KMT2AALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |