Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471235 | 0.91 | MEN1 (0.46) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634466 | 0.89 | MEN1 (0.48) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21015217 | 0.89 | LMNA (0.45) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634640 | 0.85 | LMNA (0.53) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634649 | 0.84 | MEN1 (0.50) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634645 | 0.79 | LMNA (0.50) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634646 | 0.79 | DRD3 (0.49) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21015218 | 0.78 | LMNA (0.53) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL21015216 | 0.78 | LMNA (0.46) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL19634720 | 0.78 | LMNA (0.48) | MEN1KMT2ALMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |