Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21015339 | 0.89 | DRD3 (0.47) | DRD3DRD2KCNA5MEN1KMT2A | |
| SCHEMBL19634640 | 0.84 | LMNA (0.53) | MEN1KMT2APARP1LMNATSHR | |
| SCHEMBL19634466 | 0.81 | MEN1 (0.48) | DRD3DRD2MEN1KMT2APARP1 | |
| SCHEMBL21015336 | 0.81 | DRD3 (0.46) | DRD3DRD2KCNA5MEN1KMT2A | |
| SCHEMBL21015337 | 0.80 | DRD3 (0.48) | DRD3DRD2KCNA5MEN1KMT2A | |
| SCHEMBL19634467 | 0.79 | MEN1 (0.46) | MEN1KMT2APARP1LMNATSHR | |
| SCHEMBL19634645 | 0.78 | LMNA (0.50) | MEN1KMT2APARP1LMNATSHR | |
| SCHEMBL21015338 | 0.76 | DRD3 (0.50) | DRD3DRD2KCNA5MEN1KMT2A | |
| SCHEMBL19634642 | 0.76 | DRD3 (0.50) | DRD3DRD2KCNA5MEN1KMT2A | |
| SCHEMBL19634720 | 0.76 | LMNA (0.48) | MEN1KMT2APARP1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |