Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18628615 | 0.83 | PIK3CD (0.38) | NAMPT | |
| SCHEMBL23471143 | 0.78 | RECQL (0.41) | CACNA1H | |
| SCHEMBL14932882 | 0.77 | CACNA1H (0.36) | CACNA1HADORA2ABCHE | |
| SCHEMBL12028700 | 0.77 | HPGD (0.46) | CACNA1HBCHE | |
| SCHEMBL8964 | 0.77 | MEN1 (0.50) | CACNA1HBCHE | |
| SCHEMBL14902252 | 0.75 | CACNA1H (0.35) | CACNA1HBCHE | |
| SCHEMBL13194845 | 0.75 | LMNA (0.41) | — | |
| SCHEMBL4866354 | 0.75 | ALDH1A1 (0.48) | CACNA1HBCHE | |
| SCHEMBL8437331 | 0.75 | CACNA1H (0.35) | CACNA1HBCHE | |
| SCHEMBL993141 | 0.75 | CACNA1H (0.35) | CACNA1HBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |