Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.66 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.64 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471000 | 0.87 | SLC7A5 (0.65) | SLC7A5LOXL2CYP4F2CYP4A11TDP1 | |
| SCHEMBL10174530 | 0.85 | SLC7A5 (0.63) | SLC7A5LOXL2CYP4F2CYP4A11KMT2A | |
| SCHEMBL28922549 | 0.85 | LOXL2 (0.70) | SLC7A5LOXL2CYP4F2CYP4A11HTR2C | |
| SCHEMBL19634285 | 0.84 | LOXL2 (0.69) | SLC7A5LOXL2CYP4F2CYP4A11HTR2C | |
| SCHEMBL134602 | 0.84 | SLC7A5 (0.60) | SLC7A5CYP4F2CYP4A11TDP1CA1 | |
| SCHEMBL6736568 | 0.83 | SLC7A5 (0.59) | SLC7A5CYP4F2CYP4A11TDP1CA1 | |
| SCHEMBL29404963 | 0.83 | SLC7A5 (0.59) | SLC7A5CYP4F2CYP4A11TDP1CA1 | |
| SCHEMBL6537065 | 0.83 | SLC7A5 (0.59) | SLC7A5CYP4F2CYP4A11TDP1CA1 | |
| SCHEMBL25026558 | 0.83 | SLC7A5 (0.60) | SLC7A5LOXL2CYP4F2CYP4A11TDP1 | |
| SCHEMBL2450193 | 0.82 | LOXL2 (0.71) | LOXL2CYP4F2CYP4A11CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |