Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.65 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.55 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10174530 | 0.88 | SLC7A5 (0.63) | SLC7A5CYP4F2CYP4A11LOXL2KMT2A | |
| SCHEMBL134602 | 0.87 | SLC7A5 (0.60) | SLC7A5CYP4F2CYP4A11TDP1KMT2A | |
| SCHEMBL19634575 | 0.87 | SLC7A5 (0.66) | SLC7A5CYP4F2CYP4A11LOXL2TDP1 | |
| SCHEMBL6736568 | 0.85 | SLC7A5 (0.59) | SLC7A5CYP4F2CYP4A11TDP1KMT2A | |
| SCHEMBL29404963 | 0.85 | SLC7A5 (0.59) | SLC7A5CYP4F2CYP4A11TDP1KMT2A | |
| SCHEMBL6537065 | 0.85 | SLC7A5 (0.59) | SLC7A5CYP4F2CYP4A11TDP1KMT2A | |
| SCHEMBL19634279 | 0.85 | CYP4F2 (0.56) | SLC7A5CYP4F2CYP4A11PRKCAPRKCD | |
| SCHEMBL25026558 | 0.85 | SLC7A5 (0.60) | SLC7A5CYP4F2CYP4A11LOXL2TDP1 | |
| SCHEMBL9770912 | 0.84 | CYP4F2 (0.57) | CYP4F2CYP4A11TDP1LMNAL3MBTL1 | |
| SCHEMBL23471250 | 0.84 | SLC7A5 (0.59) | SLC7A5CYP4F2CYP4A11PRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |