Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634739 | 0.89 | DRD3 (0.55) | DRD3DRD2KCNA5 | |
| SCHEMBL19634643 | 0.87 | DRD3 (0.52) | DRD3DRD2KCNA5MEN1KMT2A | |
| SCHEMBL21015337 | 0.83 | DRD3 (0.48) | DRD3DRD2KCNA5MEN1KMT2A | |
| SCHEMBL19634709 | 0.81 | MEN1 (0.56) | DRD3DRD2MEN1KMT2ALMNA | |
| SCHEMBL19634724 | 0.80 | LOXL2 (0.53) | DRD3DRD2MEN1KMT2ALMNA | |
| SCHEMBL19634706 | 0.79 | PARP1 (0.58) | MEN1KMT2ALMNATSHRMAPK1 | |
| SCHEMBL2322582 | 0.78 | SMN1; SMN2 (0.57) | MEN1KMT2ALMNATSHRMAPK1 | |
| SCHEMBL19634743 | 0.78 | MEN1 (0.52) | DRD3DRD2MEN1KMT2ALMNA | |
| SCHEMBL19634738 | 0.76 | DRD3 (0.52) | DRD3DRD2KCNA5MEN1KMT2A | |
| SCHEMBL19634649 | 0.76 | MEN1 (0.50) | DRD3DRD2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |