Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634703 | 0.86 | HPGD (0.63) | LOXL2KMT2AL3MBTL1HPGDTDP1 | |
| SCHEMBL19634742 | 0.82 | LOXL2 (0.54) | LOXL2KMT2AL3MBTL1HPGDTDP1 | |
| SCHEMBL929805 | 0.82 | LOXL2 (0.60) | LOXL2KMT2AL3MBTL1NPC1LMNA | |
| Hydrochloric Acid SCHEMBL22261342 | 0.81 | LOXL2 (0.58) | LOXL2KMT2AL3MBTL1NPC1LMNA | |
| SCHEMBL19634729 | 0.80 | HDAC3 (0.47) | KMT2AL3MBTL1PARP1HPGDTDP1 | |
| SCHEMBL13715334 | 0.77 | LOXL2 (0.62) | LOXL2KMT2AL3MBTL1NPC1LMNA | |
| SCHEMBL15071548 | 0.77 | HPGD (0.59) | KMT2AL3MBTL1HPGDMEN1ALDH1A1 | |
| SCHEMBL5109753 | 0.77 | LOXL2 (0.54) | LOXL2KMT2APARP1NPC1LMNA | |
| SCHEMBL19634721 | 0.76 | LOXL2 (0.47) | LOXL2KMT2AL3MBTL1NPC1LMNA | |
| SCHEMBL19634294 | 0.75 | LOXL2 (0.56) | LOXL2KMT2APARP1MEN1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |