Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25241014 | 0.80 | — | — | |
| SCHEMBL19634782 | 0.79 | — | — | |
| SCHEMBL2622408 | 0.76 | LMNA (0.40) | CYP1A2POLBCYP2C19 | |
| SCHEMBL12419716 | 0.74 | NOS3 (0.34) | CYP1A2POLBCYP2C19 | |
| SCHEMBL2817008 | 0.73 | PIK3CG (0.38) | CYP1A2POLBCYP2C19 | |
| SCHEMBL28930726 | 0.73 | CYP1A2 (0.35) | CYP1A2POLBCYP2C19 | |
| SCHEMBL21241075 | 0.73 | CYP1A2 (0.32) | CYP1A2POLBCYP2C19 | |
| SCHEMBL23403686 | 0.73 | KDM4E (0.32) | CYP1A2POLBCYP2C19 | |
| SCHEMBL13487955 | 0.70 | KDM4E (0.36) | CYP1A2POLBCYP2C19 | |
| SCHEMBL24117727 | 0.70 | KDM4E (0.33) | CYP1A2POLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201150-A1 | ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2017-11-23 | — | — | WO | disclosed |