Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.33 |
| ▸ | FPR2 | P25090 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17754037 | 0.85 | MEN1 (0.50) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL14901855 | 0.80 | MEN1 (0.64) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL22636637 | 0.79 | TGM2 (0.43) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL19635146 | 0.79 | ABCB1 (0.33) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL19962186 | 0.77 | MEN1 (0.49) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL19962190 | 0.77 | MEN1 (0.49) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL19962187 | 0.76 | MEN1 (0.56) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL20288666 | 0.73 | TGM2 (0.39) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL16081224 | 0.72 | MEN1 (0.57) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL12763951 | 0.71 | POLB (0.50) | MEN1BLMKMT2AUSP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201531-A1 | PHOTOACTIVE FLUOROPHORES AND METHODS OF IN VIVO LABELING | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2017-11-23 | — | — | WO | disclosed |