SCHEMBL20288666

SCHEMBL20288666

C=C(C)C(=O)OCCN(C)C(=O)c1ccccc1-c1c2ccc(=[N+](CC)CC)cc-2oc2cc(N3CCCCC3)ccc12

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 1/20 0.39
▸ FPR2 P25090 4/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ USP2 O75604 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ PPARG P37231 1/20 0.36
▸ BLM P54132 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ RXFP1 Q9HBX9 1/20 0.36
▸ NCOR2 Q9Y618 1/20 0.36
▸ CHRM1 P11229 2/20 0.36
▸ AVPR2 P30518 3/20 0.35
▸ MMP2 P08253 5/20 0.34
▸ NPY4R P50391 3/20 0.33
▸ ABCB1 P08183 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20288667 0.87 MEN1 (0.50) TGM2FPR2MEN1USP2POLB
SCHEMBL20288665 0.78 FPR2 (0.41) TGM2FPR2MEN1USP2POLB
SCHEMBL13609836 0.77 USP2 (0.52) TGM2FPR2MEN1USP2POLB
SCHEMBL19494775 0.76 ABCB1 (0.42) TGM2FPR2MEN1USP2POLB
SCHEMBL17532633 0.76 MEN1 (0.51) TGM2FPR2MEN1USP2POLB
SCHEMBL17693122 0.75 MEN1 (0.50) TGM2FPR2MEN1USP2POLB
SCHEMBL19655008 0.75 ABCB1 (0.42) TGM2FPR2MEN1USP2POLB
SCHEMBL22636637 0.75 TGM2 (0.43) TGM2FPR2MEN1USP2POLB
SCHEMBL12763952 0.74 MEN1 (0.44) TGM2FPR2MEN1USP2POLB
SCHEMBL19655007 0.74 ABCB1 (0.40) TGM2FPR2MEN1USP2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180171043-A1 XANTHENE-BASED POLYMERIC COMPOUNDS, A RESIN COMPOSITION FOR COLOR FILTER COMPRISING SAME AND A COLOR FILTER USING SAME KYUNG-IN SYBTHETIC CO., LTD. (KR) 2018-06-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180171043-A1 XANTHENE-BASED POLYMERIC COMPOUNDS, A RESIN COMPOSITION FOR COLOR FILTER COMPRISING SAME AND A COLOR FILTER USING SAME DCXR, SUN2, ABCC1 TGM2 2332/4885FPR2 11/4885MEN1 3901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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