SCHEMBL19636068

SCHEMBL19636068

Cc1cccccc2c(cc1)[nH]c1cc3c(cc12)C(C)(C)c1ccccc1-3

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 7/20 0.45
PGR P06401 2/20 0.40
AHR P35869 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
ATM Q13315 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
BCHE P06276 1/20 0.35
CCNB2 O95067 1/20 0.35
CDK1 P06493 1/20 0.35
CCNB1 P14635 1/20 0.35
GSK3B P49841 1/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520180 0.89 AHR (0.52) KIF11PGRAHRMEN1KMT2A
SCHEMBL31619 0.89 AHR (0.52) KIF11PGRAHRMEN1KMT2A
SCHEMBL29438560 0.89 AHR (0.52) KIF11PGRAHRMEN1KMT2A
SCHEMBL15413860 0.86 AHR (0.39) KIF11PGRAHRMEN1KMT2A
SCHEMBL21376967 0.85 KIF11 (0.45) KIF11PGRMEN1KMT2ANPC1
SCHEMBL21346765 0.85 KIF11 (0.57) KIF11PGRAHRMEN1KMT2A
SCHEMBL29506376 0.83 AHR (0.52) KIF11PGRAHRMEN1KMT2A
SCHEMBL31680 0.83 AHR (0.52) KIF11PGRAHRMEN1KMT2A
SCHEMBL22106242 0.83 PDK2 (0.41) KIF11PGRAHRMEN1KMT2A
SCHEMBL14979109 0.83 CDK4 (0.39) PGRAHRNPC1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017200320-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF 덕산네오룩스 주식회사 2017-11-23 WO disclosed