SCHEMBL21346765

SCHEMBL21346765

Cc1ccc2c(c1)C(C)(C)c1cc3c(cc1-2)[nH]c1ccccc13

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 7/20 0.57
AHR P35869 1/20 0.47
PGR P06401 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
KDM4E B2RXH2 3/20 0.42
MAPT P10636 3/20 0.42
ATM Q13315 1/20 0.42
ALDH1A1 P00352 3/20 0.41
GAA P10253 2/20 0.41
LMNA P02545 1/20 0.41
ALOX12 P18054 1/20 0.41
HSD17B10 Q99714 2/20 0.40
CDK4 P11802 1/20 0.40
CCND1 P24385 1/20 0.40
CAMK2B Q13554 1/20 0.40
CAMK2G Q13555 1/20 0.40
CAMK2D Q13557 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31619 0.87 AHR (0.52) KIF11AHRPGRMEN1KMT2A
SCHEMBL29520180 0.87 AHR (0.52) KIF11AHRPGRMEN1KMT2A
SCHEMBL29438560 0.87 AHR (0.52) KIF11AHRPGRMEN1KMT2A
SCHEMBL19636068 0.85 KIF11 (0.45) KIF11AHRPGRMEN1KMT2A
SCHEMBL1760348 0.84 AHR (0.46) KIF11AHRPGRMEN1KMT2A
SCHEMBL1760310 0.83 AHR (0.45) KIF11AHRPGRMEN1KMT2A
SCHEMBL802645 0.83 AHR (0.59) KIF11AHRPGRMEN1KMT2A
SCHEMBL12178081 0.82 AHR (0.44) KIF11AHRPGRMEN1KMT2A
SCHEMBL18351619 0.82 AHR (0.53) KIF11AHRPGRMEN1KMT2A
SCHEMBL15434243 0.82 AHR (0.46) KIF11AHRPGRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021074106-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-04-22 WO disclosed
WO-2019170729-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed
WO-2019170691-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed