Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET3 | O43151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.33 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.33 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075244 | 0.78 | HRH3 (0.32) | — | |
| SCHEMBL16078761 | 0.78 | KDM4E (0.34) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL19595596 | 0.77 | JAK3 (0.32) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL25365469 | 0.74 | MEN1 (0.32) | KMT2A | |
| SCHEMBL31394980 | 0.73 | CNR2 (0.33) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL24821408 | 0.73 | TET3 (0.32) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL31599560 | 0.72 | LTA4H (0.31) | — | |
| SCHEMBL15007869 | 0.72 | — | — | |
| SCHEMBL20738738 | 0.72 | JAK3 (0.40) | KMT2A | |
| SCHEMBL16380184 | 0.71 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198050-A1 | 5-AMINOPYRAZOLE CARBOXAMIDE DERIVATIVE AS BTK INHIBITOR AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF | 浙江予川医药科技有限公司 | 2017-11-23 | — | — | WO | disclosed |