Sugi Predict

Sugi Predict / Compounds / SCHEMBL19636334

SCHEMBL19636334

SCHEMBL19636334

CC1(C)c2cc3c(cc2-c2ccc4ccccc4c21)[nH]c1c2ccccc2ccc31

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 2/20 0.48
▸ KDM4E B2RXH2 6/20 0.39
▸ ALDH1A1 P00352 4/20 0.39
▸ HTT P42858 3/20 0.39
▸ HPGD P15428 3/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ CDC25A P30304 1/20 0.36
▸ CDC25C P30307 1/20 0.36
▸ KMT2A Q03164 4/20 0.34
▸ MEN1 O00255 3/20 0.34
▸ CDK4 P11802 5/20 0.33
▸ CCND1 P24385 5/20 0.33
▸ MAPT P10636 2/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ BCHE P06276 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ SIRT2 Q8IXJ6 1/20 0.33
▸ SIRT1 Q96EB6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21942157 0.87 MEN1 (0.35) KIF11KDM4EALDH1A1HTTHPGD
SCHEMBL21942156 0.87 AHR (0.45) KIF11KDM4EALDH1A1HTTHPGD
SCHEMBL21128436 0.86 KIF11 (0.49) KIF11KDM4EALDH1A1HTTHPGD
SCHEMBL18665887 0.83 KIF11 (0.43) KIF11KDM4EALDH1A1HTTHPGD
SCHEMBL19636278 0.82 CDK4 (0.39) KDM4EALDH1A1HTTHPGDSMN1; SMN2
SCHEMBL19382949 0.82 KIF11 (0.43) KIF11KDM4EALDH1A1HTTHPGD
SCHEMBL19636065 0.82 AHR (0.45) KIF11KDM4EALDH1A1HTTHPGD
SCHEMBL19636282 0.82 KIF11 (0.50) KIF11KDM4EALDH1A1HTTHPGD
SCHEMBL19636225 0.81 KIF11 (0.49) KIF11KDM4EALDH1A1HTTHPGD
SCHEMBL23077209 0.79 CCNE2 (0.36) KIF11ALDH1A1HPGDSMN1; SMN2CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190185411-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2019-06-20 — — US disclosed
US-20190131543-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2019-05-02 — — US disclosed
WO-2017200320-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF 덕산네오룩스 주식회사 2017-11-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190185411-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF PIEZO1, ORAI2, EXOC1 KIF11 2727/4885KDM4E 1772/4885ALDH1A1 2268/4885
US-20190131543-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF ORC3, PIEZO1, ORAI2 KIF11 3641/4885KDM4E 741/4885ALDH1A1 2829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.