Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19636576 | 0.87 | CNR1 (0.50) | CNR2ALDH1A1LMNANPSR1TAS2R14 | |
| SCHEMBL28183374 | 0.83 | CNR2 (0.55) | CNR2ALDH1A1LMNANPSR1TAS2R14 | |
| SCHEMBL19636592 | 0.83 | CNR2 (0.55) | CNR2ALDH1A1LMNANPSR1TAS2R14 | |
| SCHEMBL19636716 | 0.82 | CYP1A2 (0.41) | CNR2ALDH1A1LMNANPSR1HTT | |
| SCHEMBL19636580 | 0.81 | CNR2 (0.38) | CNR2ALDH1A1LMNANPSR1CNR1 | |
| SCHEMBL19636448 | 0.80 | KMT2A (0.58) | ALDH1A1LMNATAS2R14HTTPSEN1 | |
| SCHEMBL19636450 | 0.77 | ALDH1A1 (0.46) | CNR2ALDH1A1LMNANPSR1CNR1 | |
| SCHEMBL2958329 | 0.73 | CNR2 (0.57) | CNR2TAS2R14MCHR1CNR1PSEN1 | |
| SCHEMBL14470257 | 0.73 | ALDH1A1 (0.69) | CNR2ALDH1A1LMNANPSR1TAS2R14 | |
| SCHEMBL19636538 | 0.73 | CDK4 (0.47) | ALDH1A1LMNANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197670-A1 | METHOD FOR SYNTHESIZING 1,2-DIMETHYLENE CYCLOBUTANE CHIRAL COMPOUND | 中国科学院福建物质结构研究所 | 2017-11-23 | — | — | WO | disclosed |