Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19636459 | 0.80 | CNR2 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19636576 | 0.79 | CNR1 (0.50) | KMT2AMEN1PSEN1PSEN2APH1B | |
| SCHEMBL19636450 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL19636716 | 0.72 | CYP1A2 (0.41) | HSD17B10MAPTALDH1A1LMNASTAT3 | |
| SCHEMBL6993704 | 0.68 | SMN1; SMN2 (0.54) | KMT2AMEN1SMN1; SMN2MAPTTP53 | |
| SCHEMBL19636580 | 0.68 | CNR2 (0.38) | KMT2AMEN1PSEN1PSEN2APH1B | |
| SCHEMBL5515401 | 0.67 | PSEN1 (1.00) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5524800 | 0.67 | PSEN1 (1.00) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19392334 | 0.66 | KMT2A (0.75) | KMT2AMEN1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL31059283 | 0.65 | KMT2A (0.53) | KMT2AMEN1HSD17B10SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197670-A1 | METHOD FOR SYNTHESIZING 1,2-DIMETHYLENE CYCLOBUTANE CHIRAL COMPOUND | 中国科学院福建物质结构研究所 | 2017-11-23 | — | — | WO | disclosed |