Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 6/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 10/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21624572 | 0.81 | MEN1 (0.65) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7775575 | 0.80 | MEN1 (0.61) | MEN1THRBHTTKMT2AMAPT | |
| Methyl Alcohol SCHEMBL22589089 | 0.80 | NAAA (0.51) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL1972096 | 0.80 | MEN1 (0.61) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6255301 | 0.80 | MEN1 (0.61) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6129417 | 0.80 | MEN1 (0.61) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL572406 | 0.80 | MEN1 (0.61) | MEN1THRBHTTKMT2AMAPT | |
| Ethylene Glycol SCHEMBL27888485 | 0.80 | MEN1 (0.45) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6548864 | 0.80 | NAAA (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL22709126 | 0.80 | NAAA (0.50) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201352-A1 | MRNA COMBINATION THERAPY FOR THE TREATMENT OF CANCER | MODERNATX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |