Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154346 | 0.78 | MEN1 (0.71) | MEN1KMT2AALDH1A1ADORA2AADORA1 | |
| SCHEMBL1449744 | 0.75 | CDC7 (0.58) | ALDH1A1ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL29518891 | 0.75 | MEN1 (0.67) | MEN1KMT2AALDH1A1ADORA2AADORA1 | |
| SCHEMBL1853759 | 0.73 | CDC7 (0.60) | MEN1KMT2AALDH1A1ADORA2AADORA1 | |
| SCHEMBL19638048 | 0.72 | MYC (0.38) | MEN1KMT2AALDH1A1ADORA2AADORA1 | |
| SCHEMBL1848871 | 0.71 | HSD17B10 (0.64) | MEN1KMT2AALDH1A1ADORA2AADORA1 | |
| SCHEMBL22331510 | 0.71 | ADORA1 (0.51) | ADORA2AADORA1 | |
| SCHEMBL19637950 | 0.71 | TGFBR1 (0.45) | ALDH1A1ADORA2AADORA1ADORA2BHSD17B10 | |
| SCHEMBL19638228 | 0.70 | MYC (0.44) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL1850971 | 0.70 | TGFBR1 (0.51) | ALDH1A1KDM4EMAPTCYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110198939-B | Modulators of adenosine A3 receptors | 帕罗生物制药有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-107207445-B | Adenosine A3Modulators of receptors | 帕罗生物制药有限公司 | 2021-03-16 | — | — | CN | disclosed |
| EP-3581572-B1 | ADENOSINE A3 RECEPTOR MODULATORS | PALOBIOFARMA SL (ES) | 2020-11-25 | — | — | EP | disclosed |
| US-10744125-B2 | Adenosine A3 receptor modulators | PALOBIOFARMA, S.L. (ES) | 2020-08-18 | — | — | US | disclosed |
| EP-3248964-B1 | THIAZOLE MODULATORS OF A3 ADENOSINE RECEPTORS | PALOBIOFARMA SL (ES) | 2019-07-17 | — | — | EP | disclosed |
| US-10238637-B2 | Modulators of the adenosine A3 receptors | PALOBIOFARMA, S.L. (ES) | 2019-03-26 | — | — | US | disclosed |
| US-20180263963-A1 | MODULATORS OF THE ADENOSINE A3 RECEPTORS | PALOBIOFARMA, S.L. (ES) | 2018-09-20 | — | — | US | disclosed |
| EP-3248964-A1 | THIAZOLE MODULATORS OF A3 ADENOSINE RECEPTORS | PALOBIOFARMA S.L. (ES) | 2017-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180263963-A1 | MODULATORS OF THE ADENOSINE A3 RECEPTORS | ADORA3, ADORA2A, ADORA1 | MEN1 3374/4885KMT2A 4093/4885ALDH1A1 483/4885 |
| US-10744125-B2 | Adenosine A3 receptor modulators | ADORA3, ADORA2A, ADORA1 | MEN1 3716/4885KMT2A 3418/4885ALDH1A1 434/4885 |
| US-10238637-B2 | Modulators of the adenosine A3 receptors | ADORA3, ADORA2A, ADORA1 | MEN1 3374/4885KMT2A 4093/4885ALDH1A1 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.