SCHEMBL19639072

SCHEMBL19639072

c1ccc(-c2ccc(-c3nc(-n4c5ccccc5c5c6c7ccccc7n(-c7ccccc7)c6ccc54)nc4ccc(-c5ccccc5)cc34)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.40
ALDH1A1 P00352 5/20 0.40
NPSR1 Q6W5P4 3/20 0.40
HPGD P15428 3/20 0.40
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 5/20 0.40
ATM Q13315 3/20 0.40
LMNA P02545 2/20 0.38
CASP1 P29466 2/20 0.37
CASP7 P55210 2/20 0.37
USP2 O75604 1/20 0.37
S1PR2 O95136 1/20 0.37
KMT2A Q03164 1/20 0.37
HIF1A Q16665 1/20 0.37
PIK3CD O00329 1/20 0.37
PIK3CA P42336 1/20 0.37
PIK3CB P42338 1/20 0.37
MTOR P42345 1/20 0.37
PIK3CG P48736 1/20 0.37
MAPK1 P28482 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19653978 1.00 KDM4E (0.40) KDM4EALDH1A1NPSR1HPGDMAPT
SCHEMBL19653943 0.98 KDM4E (0.40) KDM4EALDH1A1NPSR1HPGDMAPT
SCHEMBL19654029 0.95 KDM4E (0.38) KDM4EALDH1A1NPSR1HPGDMAPT
SCHEMBL19653962 0.95 KDM4E (0.39) KDM4EALDH1A1NPSR1HPGDMAPT
SCHEMBL20152131 0.95 KDM4E (0.43) KDM4EALDH1A1NPSR1HPGDMAPT
SCHEMBL19654050 0.93 PIK3CD (0.39) KDM4EALDH1A1NPSR1HPGDMAPT
SCHEMBL19654028 0.92 PIK3CD (0.37) KDM4EALDH1A1NPSR1HPGDMAPT
SCHEMBL26226398 0.92 KDM4E (0.42) KDM4EALDH1A1NPSR1MAPTL3MBTL1
SCHEMBL26226424 0.92 KDM4E (0.42) KDM4EALDH1A1NPSR1MAPTL3MBTL1
SCHEMBL19654021 0.92 KDM4E (0.42) KDM4EALDH1A1NPSR1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4231804-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-08-23 EP disclosed
US-11711977-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-11711977-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-11711977-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-20220399517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 US disclosed
US-20210193934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-24 US disclosed
US-20210193934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-24 US disclosed
US-10985328-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-20 US disclosed
US-10985328-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-20 US disclosed
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220399517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSGEP KDM4E 2859/4885ALDH1A1 1043/4885NPSR1 3142/4885
US-10985328-B2 Organic electroluminescent materials and devices AZI2, INMT, PIR KDM4E 1575/4885ALDH1A1 1314/4885NPSR1 4448/4885
US-11711977-B2 Organic electroluminescent materials and devices AZI2, INMT, PIR KDM4E 1575/4885ALDH1A1 1314/4885NPSR1 4448/4885
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AZI2, INMT, PIR KDM4E 1575/4885ALDH1A1 1314/4885NPSR1 4448/4885
US-20210193934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AZI2, INMT, PIR KDM4E 1575/4885ALDH1A1 1314/4885NPSR1 4448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.