Styrene

Styrene

SCHEMBL196392

C=Cc1ccccc1.OC(F)(C(F)F)C(F)(F)F

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TSHR P16473 2/20 0.54
S1PR4 O95977 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
S1PR1 P21453 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
HSD17B2 P37059 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
PDK1 Q15118 2/20 0.33
PDK2 Q15119 2/20 0.33
PDK3 Q15120 2/20 0.33
PDK4 Q16654 2/20 0.33
EGFR P00533 1/20 0.33
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
TP53 P04637 1/20 0.31
NR1H2 P55055 2/20 0.31
NR1H3 Q13133 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4917329 0.84 ALDH1A1 (0.64) ALDH1A1TSHRS1PR4LMNAMAPT
Styrene SCHEMBL6322868 0.78 ALDH1A1 (0.61) ALDH1A1TSHRHSD17B2CYP3A4TDP1
Styrene SCHEMBL6314454 0.78 ALDH1A1 (0.61) ALDH1A1TSHRHSD17B2CYP3A4TDP1
Styrene SCHEMBL27864660 0.77 ALDH1A1 (0.74) ALDH1A1TSHRLMNACYP3A4TDP1
Styrene SCHEMBL5868543 0.76 ALDH1A1 (0.82) ALDH1A1TSHRLMNAMAPTCYP3A4
Styrene SCHEMBL4259704 0.76 ALDH1A1 (0.93) ALDH1A1TSHRLMNAMAPTCYP3A4
Styrene SCHEMBL3264247 0.76 ALDH1A1 (0.52) ALDH1A1TSHRS1PR4LMNAMAPT
Styrene SCHEMBL28863342 0.74 ALDH1A1 (0.70) ALDH1A1TSHRLMNAMAPTCYP3A4
Styrene SCHEMBL29039096 0.74 ALDH1A1 (0.70) ALDH1A1TSHRMAPTEGFRCYP3A4
Styrene SCHEMBL9466768 0.74 ALDH1A1 (0.70) ALDH1A1TSHRMAPTEGFRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6794109-B2 POLYMER CONTAINING A FLUORINATED STYRENE COPOLYMER MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2004-09-21 US claimed
US-20020160297-A1 Low abosorbing resists for 157 nm lithography AIR FORCE, UNITED STATES 2002-10-31 US claimed
WO-2002069043-A2 LOW ABSORBING RESISTS FOR 157 NM LITHOGRAPHY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-09-06 WO claimed
CN-114206015-A Method for manufacturing a circuit-board structure 佳胜科技股份有限公司 2022-03-18 CN disclosed
US-8088537-B2 Resist top coat composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-01-03 US disclosed
US-20110305979-A1 RESIST TOP COAT COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-12-15 US disclosed
US-20090197200-A1 Resist top coat composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-06 US disclosed
CN-100355023-C Semiconductor fabrication apparatus and pattern formation method using the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2007-12-12 CN disclosed
US-7135273-B2 Pattern formation method MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2006-11-14 US disclosed
US-7132214-B2 Polymers and photoresist compositions for short wavelength imaging SHIPLEY COMPANY, L.L.C. (US) 2006-11-07 US disclosed
US-6872504-B2 High sensitivity X-ray photoresist MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-03-29 US disclosed
US-6864037-B2 Acrylic polymer; exposure to high energy radiation; photoresist patterns SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-08 US disclosed
US-6794109-B2 POLYMER CONTAINING A FLUORINATED STYRENE COPOLYMER MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2004-09-21 US disclosed
US-20040110091-A1 High sensitivity X-ray photoresist MASS INSTITUTE OF TECHNOLOGY (MIT) 2004-06-10 US disclosed
US-20030082479-A1 Polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-05-01 US disclosed
WO-2002091084-A2 RESIST WITH REDUCED LINE EDGE ROUGHNESS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-11-14 WO disclosed
US-20020160297-A1 Low abosorbing resists for 157 nm lithography AIR FORCE, UNITED STATES 2002-10-31 US disclosed
WO-2002069043-A2 LOW ABSORBING RESISTS FOR 157 NM LITHOGRAPHY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-09-06 WO disclosed
US-20020055061-A1 Novel polymers and photoresist compositions for short short wavelength imaging SHIPLEY COMPANY, L.L.C. 2002-05-09 US disclosed
WO-2002021213-A2 NOVEL POLYMERS AND PHOTORESIST COMPOSITIONS FOR SHORT WAVELENGTH IMAGING SHIPLEY COMPANY, L.L.C. (US) 2002-03-14 WO disclosed