Styrene

Styrene

SCHEMBL4917329

C=Cc1ccccc1.OC(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.64

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
TSHR P16473 2/20 0.64
S1PR4 O95977 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
S1PR1 P21453 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.35
HDAC8 Q9BY41 2/20 0.33
MAOB P27338 2/20 0.33
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 2/20 0.33
HSD17B2 P37059 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
NFE2L2 Q16236 1/20 0.33
CYP2C19 P33261 1/20 0.33
CYP2A6 P11509 1/20 0.33
PDK1 Q15118 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL196392 0.84 ALDH1A1 (0.54) ALDH1A1TSHRS1PR4LMNAMAPT
Styrene SCHEMBL5868543 0.83 ALDH1A1 (0.82) ALDH1A1TSHRLMNAMAPTTDP1
Styrene SCHEMBL4259704 0.83 ALDH1A1 (0.93) ALDH1A1TSHRLMNAMAPTTDP1
Styrene SCHEMBL3264247 0.82 ALDH1A1 (0.52) ALDH1A1TSHRS1PR4LMNAMAPT
Styrene SCHEMBL9466768 0.81 ALDH1A1 (0.70) ALDH1A1TSHRMAPTTDP1TP53
Styrene SCHEMBL29039096 0.81 ALDH1A1 (0.70) ALDH1A1TSHRMAPTTDP1TP53
Styrene SCHEMBL6322868 0.80 ALDH1A1 (0.61) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL11144289 0.80 ALDH1A1 (1.00) ALDH1A1TSHRLMNAMAPTTDP1
Styrene SCHEMBL4986035 0.80 ALDH1A1 (1.00) ALDH1A1TSHRLMNAMAPTTDP1
Styrene SCHEMBL369036 0.80 ALDH1A1 (1.00) ALDH1A1TSHRLMNAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080293903-A1 Optical Organic Polymer ENABLENCE TECHNOLOGIES USA INC. (CA) 2008-11-27 US disclosed
US-20080287624-A1 Process for Preparing an Optical Organic Polymer ENABLENCE TECHNOLOGIES USA INC. (CA) 2008-11-20 US disclosed
US-20080286580-A1 Polymeric Optical Waveguide ENABLENCE TECHNOLOGIES USA INC. (CA) 2008-11-20 US disclosed
WO-2006034011-A9 PROCESS FOR PREPARING AN OPTICAL ORGANIC POLYMER DU PONT (US) 2006-05-18 WO disclosed
WO-2006034011-A1 PROCESS FOR PREPARING AN OPTICAL ORGANIC POLYMER E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-03-30 WO disclosed
WO-2006032017-A1 POLYMERIC OPTICAL WAVEGUIDE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-03-23 WO disclosed
WO-2006032020-A1 OPTICAL ORGANIC POLYMER E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-03-23 WO disclosed