Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28927915 | 0.93 | TSHR (0.70) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL724296 | 0.92 | TSHR (0.72) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL1877021 | 0.92 | TSHR (0.72) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL6568101 | 0.90 | TSHR (0.51) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL11101921 | 0.90 | ALDH1A1 (0.60) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL7572485 | 0.88 | TSHR (0.68) | TSHRALDH1A1THRBPOLBAPEX1 | |
| Butanone SCHEMBL11127013 | 0.87 | TSHR (0.66) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL10758858 | 0.87 | TSHR (0.66) | TSHRALDH1A1THRBPOLBAPEX1 | |
| Methacrylic Acid SCHEMBL4865839 | 0.87 | TSHR (0.66) | TSHRALDH1A1THRBPOLBAPEX1 | |
| Methacrylic Acid SCHEMBL27388646 | 0.87 | TSHR (0.66) | TSHRALDH1A1THRBPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200085775-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING ACNE | DR. REDDY'S LABORATORIES LTD. (IN) | 2020-03-19 | — | — | US | disclosed |
| US-20170340594-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING ACNE | DR. REDDY'S LABORATORIES LTD. (IN) | 2017-11-30 | — | — | US | disclosed |