Stearic Acid

Stearic Acid

SCHEMBL19640926

CC(C)(N)CCN.CCCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.61
PPARG P37231 7/20 0.61
PPARD Q03181 7/20 0.61
PPARA Q07869 7/20 0.61
HDAC11 Q96DB2 5/20 0.61
TSHR P16473 4/20 0.61
PTPN1 P18031 3/20 0.61
FABP4 P15090 3/20 0.61
ALDH1A1 P00352 2/20 0.61
TLR2 O60603 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
KMT2A Q03164 2/20 0.61
ALOX15 P16050 2/20 0.61
HSD17B10 Q99714 2/20 0.61
SLC22A6 Q4U2R8 1/20 0.61
SLC22A8 Q8TCC7 1/20 0.61
MEN1 O00255 1/20 0.61
ESR1 P03372 1/20 0.61
PDE4A P27815 1/20 0.61
PDE3A Q14432 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Behenic Acid SCHEMBL19639124 1.00 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL3416660 0.89 GPR84 (0.65) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL3411942 0.89 GPR84 (0.65) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL28628353 0.89 GPR84 (0.65) GPR84PPARGPPARDPPARAHDAC11
Heptanoate SCHEMBL3412856 0.89 GPR84 (0.65) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL19639137 0.87 GPR84 (0.68) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL31284227 0.87 GPR84 (0.68) GPR84PPARGPPARDPPARAHDAC11
Hexanoate SCHEMBL3410844 0.87 AKR1B1 (0.64) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL7754490 0.86 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL7752439 0.86 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO LTD (JP) 2026-03-19 US disclosed
EP-4626941-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE Dow Toray Co., Ltd. (JP) 2025-10-08 EP disclosed
EP-3660098-B1 OIL-IN-WATER-TYPE EMULSION COMPOSITION, METHOD FOR PRODUCING SAME, AND USE OF SAME DOW TORAY CO LTD (JP) 2024-10-02 EP disclosed
WO-2024154369-A1 OXIDATIVE HAIR DYE 株式会社アジュバンホールディングス 2024-07-25 WO disclosed
US-12037467-B2 Oil-in-water-type emulsion composition, method for producing same, and use of same DOW TORAY CO., LTD. (JP) 2024-07-16 US disclosed
WO-2024113195-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO., LTD. (JP) 2024-06-06 WO disclosed
US-11213464-B2 Solid temporal colorimetric hydrogel cosmetic composition having flexibility by gamma-ray irradiation COSMECCA KOREA CO., LTD. (KR) 2022-01-04 US disclosed
US-20210386651-A1 METHOD OF DESIGNING FILM-FORMING AGENT OR COSMETIC CONTAINING THE SAME DOW TORAY CO LTD (JP) 2021-12-16 US disclosed
US-20200308350-A1 OIL-IN-WATER-TYPE EMULSION COMPOSITION, METHOD FOR PRODUCING SAME, AND USE OF SAME DOW TORAY CO., LTD. (JP) 2020-10-01 US disclosed
US-20200306150-A1 SOLID TEMPORAL COLORIMETRIC HYDROGEL COSMETIC COMPOSITION HAVING FLEXIBILITY BY GAMMA-RAY IRRADIATION COSMECCA KOREA CO., LTD. (KR) 2020-10-01 US disclosed
US-10731009-B2 Cured silicone particles and cosmetic incorporating same therein DOW TORAY CO., LTD. (JP) 2020-08-04 US disclosed
US-20200222300-A1 FILM-FORMING AGENT FOR COSMETICS AND COSMETICS CONTAINING SAME DOW TORAY CO., LTD. (JP) 2020-07-16 US disclosed
EP-3660098-A1 OIL-IN-WATER-TYPE EMULSION COMPOSITION, METHOD FOR PRODUCING SAME, AND USE OF SAME Dow Toray Co., Ltd. (JP) 2020-06-03 EP disclosed
EP-3646850-A1 FILM-FORMING AGENT FOR COSMETICS AND COSMETICS CONTAINING SAME Dow Toray Co., Ltd. (JP) 2020-05-06 EP disclosed
EP-3327064-B1 CURED SILICONE PARTICLES AND COSMETIC INCORPORATING SAME THEREIN DOW TORAY CO LTD (JP) 2020-04-15 EP disclosed
US-10052268-B2 Oxidative hair dye composition HOYU CO., LTD. (JP) 2018-08-21 US disclosed
US-20180215877-A1 CURED SILICONE PARTICLES AND COSMETIC INCORPORATING SAME THEREIN DOW TORAY CO., LTD. (JP) 2018-08-02 US disclosed
EP-3327064-A1 CURED SILICONE PARTICLES AND COSMETIC INCORPORATING SAME THEREIN Dow Corning Toray Co., Ltd. (JP) 2018-05-30 EP disclosed
US-20170340524-A1 OXIDATIVE HAIR DYE COMPOSITION HOYU CO., LTD. (JP) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE FOXM1, FOXK1, TAF1L GPR84 3671/4885PPARG 45/4885PPARD 2165/4885
US-20200222300-A1 FILM-FORMING AGENT FOR COSMETICS AND COSMETICS CONTAINING SAME CUTA, WASHC5, WASHC4 GPR84 1098/4885PPARG 2126/4885PPARD 3536/4885
US-20210386651-A1 METHOD OF DESIGNING FILM-FORMING AGENT OR COSMETIC CONTAINING THE SAME WASHC5, WASHC4, CUTA GPR84 1360/4885PPARG 2062/4885PPARD 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.