Monoethanolamine

Monoethanolamine

SCHEMBL1964143

NCCO.O=C(O)C(O)SSC(O)C(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MPL

The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.40
OR51E2 Q9H255 2/20 0.36
GABRR1 P24046 4/20 0.36
GSR P00390 1/20 0.33
RNPEP Q9H4A4 1/20 0.32
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
LMNA P02545 1/20 0.32
CPB2 Q96IY4 1/20 0.31
GLRA1 P23415 1/20 0.30
SLC6A9 P48067 1/20 0.30
ENPEP Q07075 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94212 0.81 TSHR (0.44) TSHRALDH1A1OR51E2LMNA
SCHEMBL8346659 0.78 TSHR (0.41) TSHRALDH1A1OR51E2LMNA
Ammonia Solution, Strong SCHEMBL8353342 0.78 TSHR (0.41) TSHRALDH1A1OR51E2LMNA
Ammonia Solution, Strong SCHEMBL714830 0.78 TSHR (0.41) TSHRALDH1A1OR51E2LMNA
SCHEMBL8351174 0.78 TSHR (0.41) TSHRALDH1A1OR51E2LMNA
Trolamine SCHEMBL8354308 0.76 KDM4E (0.34) OR51E2
Cadaverine Tartrate SCHEMBL1834853 0.76 TSHR (0.59) TSHRALDH1A1OR51E2GABRR1GSR
Cadaverine Tartrate SCHEMBL1833811 0.76 TSHR (0.59) TSHRALDH1A1OR51E2GABRR1GSR
Tartaric Acid SCHEMBL31538119 0.76 TSHR (0.59) TSHRALDH1A1OR51E2GABRR1GSR
Lactic Acid SCHEMBL22346344 0.74 TP53 (0.61) TSHRALDH1A1OR51E2GABRR1GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4593786-A1 STABLE SKIN CARE COMPOSITIONS CONTAINING A RETINOID The Procter & Gamble Company (US) 2025-08-06 EP claimed
WO-2024073219-A1 STABLE SKIN CARE COMPOSITIONS CONTAINING A RETINOID THE PROCTER & GAMBLE COMPANY (US) 2024-04-04 WO claimed
US-20240099944-A1 Stable Skin Care Compositions Containing a Retinoid THE PROCTER & GAMBLE COMPANY 2024-03-28 US claimed
US-20120171156-A1 METHODS AND COMPOUNDS FOR REDUCING ALLERGIC REACTIONS TO HAIR DYES HDS LTD. (GB) 2012-07-05 US claimed
EP-2442873-A2 METHODS AND COMPOUNDS FOR REDUCING ALLERGIC REACTIONS TO HAIR DYES Hds Limited (GB) 2012-04-25 EP claimed
WO-2010146142-A9 METHODS AND COMPOUNDS FOR REDUCING ALLERGIC REACTIONS TO HAIR DYES HDS LIMITED (GB) 2011-06-16 WO claimed
WO-2010146142-A2 METHODS AND COMPOUNDS FOR REDUCING ALLERGIC REACTIONS TO HAIR DYES HDS LIMITED (GB) 2010-12-23 WO claimed
US-5925366-A PERMEATION/BINDING AGENT, THIO CROSSLINKING AGENT, AND CHELATE COMPOUND REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-07-20 US claimed
US-5785959-A MIXTURE CONTAINING A PERMEATION/BINDING AGENT, A THIO CROSSLINKING AGENT, A CHELATING AGENT, WATER AND AN OIL REVLON CONSUMER PRODUCTS CORPORATION (US) 1998-07-28 US claimed
WO-1998006376-A1 NAIL STRENGTHENING COMPOSITIONS AND A METHOD FOR STRENGTHENING NAILS REVLON CONSUMER PRODUCTS CORPORATION (US) 1998-02-19 WO claimed
US-20250302710-A1 SKIN CARE COMPOSITIONS CONTAINING A RETINOID WITH REDUCED MALODOR THE PROCTER & GAMBLE COMPANY 2025-10-02 US disclosed
EP-4593786-A1 STABLE SKIN CARE COMPOSITIONS CONTAINING A RETINOID The Procter & Gamble Company (US) 2025-08-06 EP disclosed
EP-4464307-A1 COSMETIC COMPOSITION AND METHODS OF MAKING THE SAME MPLUS COSMETICS S.R.L. (IT) 2024-11-20 EP disclosed
US-20240374498-A1 COSMETIC COMPOSITION AND METHODS OF MAKING THE SAME MPLUS COSMETICS S.R.L. (IT) 2024-11-14 US disclosed
WO-2024073219-A1 STABLE SKIN CARE COMPOSITIONS CONTAINING A RETINOID THE PROCTER & GAMBLE COMPANY (US) 2024-04-04 WO disclosed
US-20040052748-A1 Compositions of anionic polymeric rheology modifiers and cationic materials LUBRIZOL ADVANCED MATERIALS, INC. 2004-03-18 US disclosed
US-5993794-A CONTAINING 2-7% OF THIOGLYCOLIC ACID, SALT OF THIOGLYCOLIC ACID, CYSTEINE AND/OR ACETYL CYSTEINE AND 1.5-17.5% OF DITHIODIGLYCOLIC ACID, ACID AND/OR CYSTINE TAKARA BELMONT KABUSHIKI KAISHA (JP) 1999-11-30 US disclosed
US-5925366-A PERMEATION/BINDING AGENT, THIO CROSSLINKING AGENT, AND CHELATE COMPOUND REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-07-20 US disclosed
US-5785959-A MIXTURE CONTAINING A PERMEATION/BINDING AGENT, A THIO CROSSLINKING AGENT, A CHELATING AGENT, WATER AND AN OIL REVLON CONSUMER PRODUCTS CORPORATION (US) 1998-07-28 US disclosed
WO-1998006376-A1 NAIL STRENGTHENING COMPOSITIONS AND A METHOD FOR STRENGTHENING NAILS REVLON CONSUMER PRODUCTS CORPORATION (US) 1998-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302710-A1 SKIN CARE COMPOSITIONS CONTAINING A RETINOID WITH REDUCED MALODOR RBP4, RARA, RBP1 TSHR 2099/4885ALDH1A1 20/4885OR51E2 188/4885
US-20040052748-A1 Compositions of anionic polymeric rheology modifiers and cationic materials PBRM1, PARG, PARN TSHR 3332/4885ALDH1A1 4839/4885OR51E2 1626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.