Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964499 | 1.00 | PLA2G2C (0.41) | PLA2G2CLPAR3LPAR2P2RY10PTPN1 | |
| SCHEMBL752259 | 0.90 | PLA2G2C (0.46) | PLA2G2CLPAR3LPAR2PTPN1PLA2G2D | |
| SCHEMBL1962159 | 0.86 | PTPN1 (0.49) | PLA2G2CLPAR3LPAR2PTPN1S1PR2 | |
| SCHEMBL1963907 | 0.84 | PLA2G2C (0.44) | PLA2G2CP2RY10PTPN1 | |
| SCHEMBL2311014 | 0.84 | PLA2G2C (0.44) | PLA2G2CP2RY10PTPN1 | |
| SCHEMBL4444982 | 0.84 | PLA2G2C (0.44) | PLA2G2CP2RY10PTPN1 | |
| SCHEMBL1965773 | 0.84 | PLA2G2C (0.44) | PLA2G2CP2RY10PTPN1 | |
| SCHEMBL4435691 | 0.84 | PLA2G2C (0.44) | PLA2G2CP2RY10PTPN1 | |
| SCHEMBL1962712 | 0.82 | PLA2G2C (0.43) | PLA2G2CP2RY10 | |
| SCHEMBL1964685 | 0.82 | PLA2G2C (0.43) | PLA2G2CP2RY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052718-A9 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-06-16 | — | — | WO | disclosed |