Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | FAAH | O00519 | 7/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039648 | 0.90 | CYP3A4 (0.62) | CYP2D6CYP3A4FAAHGABRA1ADRA2C | |
| SCHEMBL1035889 | 0.90 | CYP3A4 (0.65) | CYP2D6CYP3A4FAAHGABRA1ADRA2C | |
| SCHEMBL1961322 | 0.89 | CYP3A4 (0.68) | CYP2D6CYP3A4FAAHGABRA1ADRA2C | |
| SCHEMBL1077480 | 0.88 | CYP3A4 (0.65) | CYP2D6CYP3A4FAAHGABRA1ADRA2C | |
| SCHEMBL1076479 | 0.87 | CYP2D6 (0.54) | CYP2D6CYP3A4FAAHGABRA1ADRA2C | |
| SCHEMBL1076482 | 0.87 | CYP2D6 (0.54) | CYP2D6CYP3A4FAAHGABRA1ADRA2C | |
| SCHEMBL1039403 | 0.87 | CYP3A4 (0.65) | CYP2D6CYP3A4FAAHGABRA1ADRA2C | |
| SCHEMBL1036439 | 0.87 | CYP3A4 (0.64) | CYP2D6CYP3A4FAAHGABRA1ADRA2C | |
| SCHEMBL1078174 | 0.86 | CYP3A4 (0.64) | CYP2D6CYP3A4FAAHGABRA1ADRA2C | |
| SCHEMBL1083185 | 0.86 | CYP3A4 (0.66) | CYP2D6CYP3A4FAAHGABRA1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144159-A1 | ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | PFIZER INC | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144159-A1 | ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | FAAH, FAAH2, PAH | CYP2D6 382/4885CYP3A4 329/4885FAAH 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.