Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28361133 | 0.80 | ALDH1A1 (0.51) | RORCRARGKMT2AMEN1ALDH1A1 | |
| SCHEMBL1969701 | 0.75 | ELANE (0.49) | RORCKMT2AMEN1ALDH1A1F2 | |
| SCHEMBL17423704 | 0.69 | RORC (0.41) | RORCRARGKMT2AMEN1ALDH1A1 | |
| SCHEMBL24273242 | 0.69 | RORC (0.53) | RORC | |
| SCHEMBL16884641 | 0.68 | RORC (0.53) | RORC | |
| SCHEMBL7307538 | 0.68 | KDM4E (0.46) | RORCKMT2AALDH1A1 | |
| SCHEMBL21324100 | 0.67 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1MAPTELANE | |
| SCHEMBL16516519 | 0.66 | MAP3K14 (0.44) | RORCRARGPTGER1DYRK1A | |
| SCHEMBL7297551 | 0.66 | RORC (0.40) | RORCKMT2AMEN1ALDH1A1 | |
| SCHEMBL21816286 | 0.66 | MAPT (0.55) | RORCKMT2AMEN1ALDH1A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |