SCHEMBL196431

SCHEMBL196431

CCCCCCc1ccccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.58
TAAR1 Q96RJ0 3/20 0.52
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
AOC3 Q16853 1/20 0.48
HTT P42858 1/20 0.47
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
CHRM2 P08172 1/20 0.46
PNMT P11086 1/20 0.45
IDO1 P14902 1/20 0.45
BID P55957 3/20 0.45
MCL1 Q07820 3/20 0.45
BCL2L1 Q07817 2/20 0.45
BAK1 Q16611 2/20 0.45
KAT8 Q9H7Z6 2/20 0.45
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
EP300 Q09472 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4829328 1.00 LIPG (0.58) LIPGTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL5271594 1.00 LIPG (0.58) LIPGTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL28250901 1.00 LIPG (0.58) LIPGTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL5598971 1.00 LIPG (0.58) LIPGTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL5599139 1.00 LIPG (0.58) LIPGTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL3694247 1.00 LIPG (0.58) LIPGTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL19391066 1.00 LIPG (0.58) LIPGTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL11658176 1.00 LIPG (0.58) LIPGTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL31444780 1.00 LIPG (0.58) LIPGTAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL31445158 0.98 LIPG (0.56) LIPGTAAR1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716296-B Efficient halogenation synthesis method of alkyl halide 润药仁智(北京)科技有限公司 2023-12-12 CN disclosed
CN-114716296-A Efficient halogenation synthesis method of alkyl halide 北京大学 2022-07-08 CN disclosed
EP-3728237-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 EP disclosed
CN-111440053-A Industrial production method of cyclopropylmethyl cyclohexyl difluorobiphenyl compounds 西安瑞联新材料股份有限公司 2020-07-24 CN disclosed
EP-2989070-B1 IMPROVED FULLERENE DERIVATIVES AND RELATED MATERIALS, METHODS AND DEVICES MERCK PATENT GMBH (DE) 2019-08-14 EP disclosed
US-10361371-B2 Fullerene derivatives, and related materials, methods and devices NANO-C, INC. (US) 2019-07-23 US disclosed
EP-2527314-B1 Process for preparation of phenyl carbamate derivatives BIO-PHARM SOLUTIONS CO LTD (KR) 2017-10-04 EP disclosed
EP-2797878-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO LTD (KR) 2017-08-16 EP disclosed
US-20170098775-A1 FULLERENE DERIVATIVES, AND RELATED MATERIALS, METHODS AND DEVICES NANO-C, INC. 2017-04-06 US disclosed
EP-2797880-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY BIO-PHARM SOLUTIONS CO LTD (KR) 2017-03-01 EP disclosed
EP-0409689-B1 A process for the purification of 1,1-bis(4-chlorophenyl)-2,2,2-trichloroethanol ATOCHEM ELF SA (FR) 1995-03-22 EP disclosed
US-5156918-A SELF-ASSEMBLED SUPER LATTICES NORTHWESTERN UNIVERSITY (US) 1992-10-20 US disclosed
US-5081319-A Isolation and purification SOCIEDAD ESPANOLA DE DESARROLLOS QUIMICOS S.A. (ES) 1992-01-14 US disclosed
EP-0178185-B1 NOVEL AROMATIC POLYMERS RAYCHEM CORPORATION (a Delaware corporation) (US) 1991-04-10 EP disclosed
EP-0409689-A2 A process for the purification of 1,1-bis(4-chlorophenyl)-2,2,2-trichloroethanol ELF ATOCHEM S.A. (FR) 1991-01-23 EP disclosed
EP-0336240-A2 Poly(arylene sulphides) with lowered temperature of crystallization and process for preparing them BAYER AG (DE) 1989-10-11 EP disclosed
US-4868271-A POLYETHER KETONES RAYCHEM CORPORATION (US) 1989-09-19 US disclosed
WO-1986002368-A1 AROMATIC POLY(ETHER KETONES) HAVING IMIDE, AMIDE, ESTER, AZO, QUINOXALINE, BENZIMIDAZOLE, BENZOXAZOLE OR BENZOTHIAZOLE GROUPS AND METHOD OF PREPARATION RAYCHEM CORPORATION (US) 1986-04-24 WO disclosed
EP-0178185-A2 Novel aromatic polymers RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 EP disclosed
US-4361498-A UNIFORM PARTICLE SIZES TOYO STAUFFER CHEMICAL CO., LTD. (JP) 1982-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10361371-B2 Fullerene derivatives, and related materials, methods and devices PPOX, OCIAD2, OCIAD1 LIPG 2265/4885TAAR1 4810/4885SLC6A2 4129/4885
US-20170098775-A1 FULLERENE DERIVATIVES, AND RELATED MATERIALS, METHODS AND DEVICES PPOX, OCIAD2, OCIAD1 LIPG 2265/4885TAAR1 4810/4885SLC6A2 4129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.