Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214909 | 0.79 | — | — | |
| SCHEMBL3620018 | 0.79 | — | — | |
| SCHEMBL2751659 | 0.76 | — | — | |
| SCHEMBL75764 | 0.76 | — | — | |
| SCHEMBL7651246 | 0.76 | — | — | |
| SCHEMBL28025627 | 0.73 | — | — | |
| Acetic Acid SCHEMBL27318830 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNATP53FGFR4 | |
| SCHEMBL4528380 | 0.73 | — | — | |
| Ethane SCHEMBL7949282 | 0.73 | — | — | |
| SCHEMBL5145577 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3463389-A2 | PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS | Sarepta Therapeutics, Inc. (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-3464306-A1 | PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS | Sarepta Therapeutics, Inc. (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-3463390-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ETEPLIRSEN | Sarepta Therapeutics, Inc. (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-3463363-A1 | PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS | Sarepta Therapeutics, Inc. (US) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017213854-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ETEPLIRSEN | SAREPTA THERAPEUTICS, INC. (US) | 2017-12-14 | — | — | WO | disclosed |
| WO-2017205513-A1 | PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS | SAREPTA THERAPEUTICS, INC. (US) | 2017-11-30 | — | — | WO | disclosed |
| WO-2017205880-A1 | PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS | SAREPTA THERAPEUTICS, INC. (US) | 2017-11-30 | — | — | WO | disclosed |
| WO-2017205879-A2 | PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS | SAREPTA THERAPEUTICS, INC. (US) | 2017-11-30 | — | — | WO | disclosed |